Chemistry International
Vol. 24, No. 5
September 2002
Highlights
from Pure and Applied Chemistry
Harmonized
Guidelines for Single- Laboratory Validation of Methods of Analysis
(IUPAC Technical Report)
by M.
Thompson, S. L. R. Ellison, and R.Wood
Pure and Applied
Chemistry, Vol. 74, No. 5, pp. 835-855 (2002)
Method
validation is one of the measures universally recognized as a necessary
part of a comprehensive system of quality assurance in analytical chemistry.
In the past, ISO, IUPAC, and AOAC International have cooperated to produce
agreed protocols or guidelines on the "design, conduct and interpretation
of method performance studies," on the "Proficiency testing
of (chemical) analytical laboratories," on "internal quality
control in analytical chemistry laboratories," and on "the
use of recovery information in analytical measurement." The Working
Group that produced these protocols/guidelines has now been mandated
by IUPAC to prepare guidelines on the single-laboratory validation of
methods of analysis. These guidelines provide minimum recommendations
on procedures that should be employed to ensure adequate validation
of analytical methods. A draft of the guidelines has been discussed
at an International Symposium on the Harmonization of Quality Assurance
Systems in Chemical Laboratory, the proceedings from which have been
published by the UK Royal Society of Chemistry.
www.iupac.org/publications/pac/2002/7405/7405x0835.html