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Pure Appl. Chem. 75(2-3), 209-221, 2003

Pure and Applied Chemistry

Vol. 75, Issue 2-3

New and old challenges in total synthesis. From concept to practice

S. Hanessian, R. Margarita, A. Hall, S. Johnstone, M. Tremblay, and L. Parlanti

Department of Chemistry, Université de Montréal, P.O. Box 6128,
Station Centre-ville, Montréal, P.Q., H3C 3J Canada

Abstract: The total synthesis of dysinosin A, a novel member of the aeruginosin group of marine natural products is discussed. The stereocontrolled synthesis also confirms the proposed structure and absolute stereochemistry of the natural product.

*Pure Appl.Chem. 75, 141�419 (2003). An issue of reviews and research papers based on lectures presented at the 23rd IUPAC International Symposium on the Chemistry of Natural Products, Florence, Italy, 28 July � 2 August 2002.


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