Syntheses of antiangiogenic or cytotoxic natural products: Fumagillin and bengacarboline*
O. Bedel, A. Haudrechy, A. Pouilhès, and Y. Langlois
Laboratoire de Synthèse des Substances Naturelles, Associé au CNRS, Université de Paris-Sud, 91405 Orsay, France
Abstract: Syntheses of fumagillol, a precursor of antiangiogenic sesquiterpene fumagillin, and of cytotoxic marine alkaloid bengacarboline are described.
Keywords: fumagillol; antiangiogenic; sesquiterpene; fumagillin; bengacarboline.
*An issue of reviews and research papers based on lectures presented at the 15th International Conference on Organic Synthesis (ICOS-15), held in Nagoya, Japan, 1-6 August 2004, on the theme of organic synthesis. Other presentations are published in this issue, pp. 1087-1296.