Chemistry International
Vol. 21, No.5, September 1999

1999, Vol. 21
No. 5 (September)
.. President's Report
.. News from IUPAC
.. Highlights from the Web
.. New Projects
.. Provisional Recommendations
.. New Books and Publications
.. Awards and Prizes
.. Conference Announcements
.. Conferences

Download the September
issue in pdf format.
(278K)

Download the September
cover in pdf format.
(52K)



CI Homepage

Chemistry International
Vol. 21, No. 5
September 1999

New Books and Publications


New Book from the Royal Society of Chemistry

Drugs: Photochemistry and Photostability.

Edited by A. Albini and E. Fasani, University of Pavia, Italy.

Since Pasteur's discovery in 1846, scientists have been aware that many drugs are photoreactive, but until recently, research in this area had been somewhat limited. However, since the introduction of acutely sensitive analytical methods, the realization of the need to identify the photochemical properties of a potential drug as early in its development as possible, and the increased attention to the phototoxic effect of drugs, more details are becoming available.

Drugs: Photochemistry and Photostability presents the basic elements of the science, and serves as an excellent introduction to this emerging field of photochemistry. Detailed experimental conditions for photostability studies are given, along with a discussion of the recently implemented International Conference on Harmonisation (ICH) Guidelines for drug photostability.

With contributions from international experts in the field and including a comprehensive literature review, this book provides all the up-to-date information needed by researchers in many fields, especially medicinal and pharmaceutical chemistry.

Contents

Photochemistry of Drugs: An Overview and Practical Problems; Medicinal Photochemistry (An Introduction with Attention to Kinetic Aspects); Photoreactivity of Selected Antimalarial Compounds in Solution and in the Solid State; Photochemistry of Diuretic Drugs in Solution; New Results on the Photoinstability of Antimycotics; Photoreactivity versus Activity of a Selected Class of Phenothiazines: A Comparative Study; Photoprocesses in Photosensitizing Drugs Containing a Benzophenone-Like Chromophore; Photostability of Coumarin; Photostabilities of Several Chemical Compounds Used as Active Ingredients in Sunscreens; An Analytical and Structural Study of the Photostability of Some Leukotriene B4 Antagonists; Molecular Mechanisms of Photosensitization Induced by Drugs on Biological Systems and Design of Photoprotective Systems; A Comparison between the Photochemical and Photosensitizing Properties of Different Drugs; Photostability of Drug Substances and Drug Products: A Validated Reference Method for Implementing the ICH Photostability Study Guidelines; The Elaboration and Application of the ICH Guideline on Photostability: A European View; Selecting the Right Source for Pharmaceutical Photostability Testing; Design and Validation Characteristics of the Environmental Chambers for Photostability Testing; Design Limits and Qualification Issues for Room-Size Solar Simulators in a GLP Environment; Actinometry: Concepts and Experiments; trans-2-Nitrocinnamaldehyde as Chemical Actinometer for the UV-A Range in Photostability Testing of Pharmaceuticals; Subject Index.

ISBN: 0 85404 743 3; viii + 326 pages; Price: GBP 59.50; Special Publication No. 225, Hardcover, 1998.

To order, contact Sales and Customer Care, The Royal Society of Chemistry, Thomas Graham House, Science Park, Milton Road, Cambridge, England CB4 0WF, UK; E-mail: [email protected]; Tel.: +44 1223 420066; Fax: +44 1223 423429; Web site: http://www.rsc.org or http://www.chemsoc.org/.

 

 

IUPAC Homepage

IUPAC

 


News and Notices - Organizations and People - Standing Committees
Divisions - Projects - Reports - Publications - Symposia - AMP - Links
Page last modified 3 October 2001.
Copyright © 1997-2001 International Union of Pure and Applied Chemistry.

Questions or comments about IUPAC, please contact the Secretariat.
Questions regarding the website, please contact [email protected]