U P A C
Organizations & People
. . CI
. . PAC
. . Macro. Symp.
. . Books
. . Solubility Data
Pure Appl. Chem.
75(10), 1453-1475, 2003
Pure and Applied Chemistry
Vol. 75, Issue 10
Ring opening of heterocycles by an arene-catalyzed lithiation*
Departamento de Química Orgánica, Facultad de Ciencias, Universidad de
Alicante, Apdo.99, 03080 Alicante, Spain
Abstract: The ring opening of different three-, four-, five-and
six-membered oxygen-, nitrogen- and sulfur-containing saturated heterocycles
using lithium and a catalytic amount of an arene (naphthalene or DTBB)
yields a series of functionalized organolithium compounds, which, by
reaction with different electrophiles, allow the preparation of polyfunctionalized
molecules in only one synthetic operation.
*Lecture presented at the 4th Florida Heterocyclic
Conference, Gainesville, Florida, 10-12 March 2003. Other presentations
are published in this issue, pp. 1403-1475.
Page last modified 01 October 2003.
Copyright © 2003 International Union of Pure and Applied Chemistry.
Questions or comments about IUPAC, please contact, the Secretariat.
Questions regarding the website, please contact web