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Pure Appl. Chem. Vol. 75, No. 10, p. vi (2003)

Pure and Applied Chemistry

Vol. 75, Issue 10

The 4th Florida Heterocyclic Conference,
Gainesville, Florida, 10-12 March 2003

> link to conference calendar

The 4th Florida Heterocyclic Conference was held at the University of Florida in Gainesville, Florida, USA from 10–12 March 2003. About 170 out-of-town participants were treated to a plethora of fascinating chemistry presented by 12 plenary lecturers.

Three contributions were presented by industrial chemists: (i) M. Butters (AstraZeneca, Process R&D, Bristol, England) described the process development of Voriconazole (broad-spectrum antifungal agent) along with Rosuvastatin (LDL cholesterol-lowering agent); (ii) J. Marcoux (Merck, Rahway, NJ) covered the development of carbo- and heterocyclizations with applications to a practical synthesis of the Cox-2 specific inhibitor Etoricoxib; (iii) S. von Unge (AstraZeneca R&D, Molndal, Sweden) dealt with the chemical development of Nexium, the “purple pill” for heartburn relief.

Other plenary lecturers included J. Bakke (Norwegian University of Trondheim, Norway) on the synthesis and reactions of nitropyridines; S. Blechert (Technische Universitat, Berlin, Germany) on domino methathesis reactions; G. Gribble (Dartmouth College, USA) on the synthesis of heterocycles from indoles; R. Grubbs (California Institute of Technology, USA) on metal alkylidene complexes for the rapid synthesis of olefins; S. Hecht (University of Virginia, USA) on the synthesis of bleomycin libraries; Norbert de Kimpe (Ghent University, Belgium) on the use of 3-halo-1-azaallylic anions in heterocyclic synthesis; S. Kobayashi (University of Tokyo, Japan) on efficient catalysis for the synthesis of heterocyclic compounds; G.S.R. Subba Rao (Indian Institute of Science, Bangalore, India) on applications of Birch reduction products in the total synthesis of natural products; and M. Yus (Universidad de Alicante, Spain) on reductive openings of heterocycles as a versatile route to functionalized organo- lithium compounds.

The conference also included a full-day short course on the fundamentals of heterocyclic chemistry and a poster session with some 30 contributions.

The Florida Heterocyclic Conference supports Arkivoc (Archive for Organic Chemistry), a free on-line refereed journal covering all aspects of organic chemistry, which is available at <http://www.arkat-usa.org>.

The 5th Florida Heterocyclic Conference will be held in Gainesville, Florida from 7–10 March 2004.

Alan Katritzk

International Advisory Committee:
A. Katritzky (USA), C.A. Ramsden (UK), C. Rees (UK), E. Scriven (USA).

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